Research Publications & Conference Presentations 2019-04-15T20:34:10+00:00

Research Publications & Conference Presentations

Early research experience:

  • Clinical Research Fellow at Universitaetsklinikum Essen, Essen, Germany, during MD preparation: 02/01/1998 – 13/08/1999:  

1. “Characterization of hCG isohormone in trophoblastic diseases and habitual abortion”.

The research involved characterization of the biological and immunological activities of hCG molecule in–vitro, using immunometric assays. The in-vivo biological activity of the molecule was determined using functional assays using Chinese hamster ovary cells transfixed with recombinant human TSH receptor as well as other cell lines transfixed with LH/hCG receptor. Comparison between the biological and immunological activity of the molecule in trophoblastic diseases, habitual abortion and in normal pregnancy was done. The results were presented in international conferences and were published in the Gynaecologic Endocrinology Journal.

i. “The human Chorionic Gonadotropins molecule from patients with Trophoblastic diseases has a high thyrotropic activity but is less active in the ovary’’ K.Kato, M.H.Mostafa, K.Mann, A.E.Schindler and R.Hoermann. Gynecol Endocrinol. 2004; 18: 269-277.

ii. “Human Chorionic Gonadotropins exhibits normal biological activity in patients with recurrent pregnancy loss”  K.Kato, M.H.Mostafa, K.Mann, A.E.Schindler, R.Hoermann. Gynecological Endocrinology. 2002; 16: 179 – 186.

2. Study of the differences in the biological and immunological activity of various commercial hCG preparations”.

The study Involved characterization of the immunological and biological differences between the different commercial hCG preparations, using different immunometric assays, Chinese hamster ovary cells transfixed with recombinant human TSH receptor as well as other cell lines transfixed with LH/hCG receptor and high performance liquid chromatography (HPLC).

The results were published in the Zentral Blatt Fuer Gynekologie Journal.

i. “Immunological and biological activity of different commercial preparations of human Chorionic Gonadotropins” K.Kato, M.H.Mostafa, K.Mann, A.E.Schindler, R.Hoermann. Zentralblatt fuer gynekologie. 2002; 124: 123 – 127.

  • Clinical research at Ain Shams University, Cairo Egypt: (06/1994 – 06/1995):

‘’The use of Visual Evoked Potential (VEP) in the detection of the central nervous system effects of preeclampsia’’.

Clinical research in the different patterns of CNS involvement in mild and severe preeclampsia as compared to normal pregnancy. This work was submitted in the thesis for the Master degree, which was evaluated and accepted in September 1995.

Infertility related publications:

  1. Review of the use of clomiphene citrate (CC) in the Assisted Reproduction Unit (ARU) – Hartlepool. Mostafa, Hany et al. European Journal of Obstetrics and Gynaecology and Reproductive Biology, 2016, Volume 206, e8 – e9.
  2. Review of performance of patients with endometriosis in in vitro fertilisation (IVF) as compared to tubal factor infertility – Retrospective cohort study. Papir M, Mostafa H. Human Reproduction. 2015, 30 (suppl 1); 269.
  3. Subfertility Audit in North Cumbria, How to shorten the NHS funded IVF waiting list’’ M.H.Mostafa, S. Shivashankar and Dr. L Hipple. Transac N of Eng Obstet Gynaecol Soc. January 2008.
  4. Depressive and Anxiety symptoms in a sample of women with unexplained infertility: Impact of Assisted Reproduction Techniques (ART) on Psychiatric Morbidity’’. Mostafa M.H, Anwar.I, Zarif NM, Abdel Aziz AA. . Journal of the Egyptian society for Ob.&Gyn. 2005. vol.1, 67- 77. Presented to the Egyptian Society for Obstetrics and Gynaecology, and North of England Ob. & Gynae. Society.
  5. Depressive and Anxiety symptoms in a sample of women with unexplained infertility: Impact of Assisted Reproduction Techniques (ART) on Psychiatric Morbidity’’. Mostafa M.H, Anwar.I, Zarif NM, Abdel Aziz AA. Transac N of Eng Obstet Gynaecol Soc. January 2006.
  6. Assessment of the value of Fallopian sperm perfusion using two different techniques versus conventional Intrauterine Insemination. Mostafa MH, Azab H, Afify N. Kasr El Aini Medical Journal. 2004, 10(5); 243 – 250.
  7. “Ultra structural and laparoscopic evaluation of the distal end of the fallopian tube in case of tubal factor infertility’’. M.E.Azzam, M. Hassan, M.H.Mostafa. Ain Shams Medical Journal, 2004; Vol.55: 837 – 854.

Obstetric related publications:

1: “Effect of perioperative oxygenation and preloading with Hartman’s solution on fetal outcome in elective C.S. at high altitude”. M.H.Mostafa and R. A. Shoukry. Ain Shams Medical Journal. 2004; Vol.55, 163 – 173.

2: “Iron therapy in iron deficiency anemia in pregnancy: intravenous route versus oral route’’. Anwar.I, Nasr El-Din MH, Mostafa MH., Elfiky AH, Zaki MM. Ain Shams Medical Journal. 2004. Vol. 55; 855 – 865.

3: “Evaluation of the role of oral Prednisolone in the treatment of intractable hyperemesis gravidarum . A randomised study.’’ M.H. Mostafa. Ain Shams Medical Journal. 2004. Vol. 55; 1271 – 1278.

4: “Obstetric, Somatic and Demographic risk factors for post partum depressive symptoms’’. Abdelazia AA, Zarif N, Sherif F, Gad E, Mostafa MH. Current Psychiatry of Ain Shams. 2004. 11(1); 42 – 47.

5: “Cervical ripening: A Randomised comparison between intracervical Foley’s catheter and intra vaginal Prostin E2’’. Mohamed M, Kolaib MH, Mostafa MH, Ghitany SM. The New Egyptian Journal of Medicine. 2001, 25(2) ; 83 – 89.

General Gynaecology related publication:

1: “A Study of Premenstrual Dysphoric Disorder (PMDD) in a sample of Egyptian Women”. M.H. Mostafa, K.M.Ismail , M.R Abou Seeda, A.H. Khalil, A.E Seif el Dawla, N.M Zarif. Journal of the Egyptian society for Ob.&Gyn. 2004. vol.30, 407- 426.

Conference Presentations:

  • Evaluation of the ARU-Hartlepool strategy for early identification, active intervention and outpatient monitoring of ovarian hyperstimulation syndrome (OHSS). H. Mostafa, B Mahroo. BFS 2016 Gateshead. Poster presentation.
  • Deep sedation (DS) with Propofol and Alfentanyl in IVF ensures greater patient and operator satisfaction and better patient experience as compared to conscious sedation. M H Mostafa and Y Attallah. BFS, 2016, Gateshead. Poster presentation.
  • Outcome of endometrial scratching in patients undergoing 3rd cycle of IVF treatment. J Moody and M H Mostafa EBCOG Glasgow 2014: oral presentation (1st prize).
  • Investigation of couple with implantation failure. J Moody and M H Mostafa. EBCOG Glasgow 2014: Poster presentation.
  • Case report: Borderline ovarian tumour in an infertile patient. R Nicholson and M H Mostafa. EBCOG Glasgow 2014: Poster presentation.
  • Single embryo transfer: an individualised approach“. Oral presentation at the BICOG, Belfast, June 2009
  • ” Subfertility audit in north Cumbria, How to reduce the IVF waiting list’’. North of England Meetting for Obstetricians and Gynaecologists, Sunderland Royal Hospital, June, 07.
  • ” Endometriosis and fertility, an update” Post graduate fertility meeting. Cumberland infirmary, Carlisle. 16 – 02 – 2007.
  • “Depression and Anxiety symptoms in patients with unexplained infertility” North of England Meeting for Obstetricians and Gynaecologists, Sunderland Royal Hospital, October, 2005.
  • “Laparoscopic Hysterectomy, an Overview” First Aseer international symposium on advances in minimally invasive surgery, Aseer, 8-10/07/03
  • “In vivo and in vitro thyroid stimulating activity in pregnant women and in patients with trophoblastic tumors’’ (Poster). 72nd Annual meeting of the American Thyroid Association, Portland, Oregon, USA. September, 1999.
  • “HCG induced thyroid dysfunction is related to hCG serum levels and source of hCG from normal or tumor origin ” (Poster).“1st Annual meeting of the American Thyroid Association, Portland, Oregon, USA. Thyroid, Annual Meeting, September 1998
  • “In-vivo and in-vitro thyrotropic activity of hCG from normal pregnancy and trophoblastic diseases’’ (Poster). Annual meeting of the German Endocrine society, Kiel, Germany. March 1999.
Click to see original poster!

Mr Mostafa presenting poster at the ESHRE 2015, Lisbon, Portugal. (Click to see poster on the ESHRE website)